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Scientists stabilize HIV construction, design potential AIDS vaccine candidates

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In a feat of bioengineering, the staff designed nanoparticles that would mimic HIV. Credit score: Picture courtesy of The Scripps Analysis Institute. Wish to catch a prison? Present a mugshot on the information. Wish to cease HIV infections? Get the immune system to acknowledge and assault the virus's tell-tale construction. That is a part of the fundamental method behind efforts at The Scripps Analysis Institute (TSRI) to design an AIDS vaccine. This technique might hinge on discovering new methods to stabilize proteins known as HIV-1 floor antigens and in designing HIV-like particles to immediate the physique to battle the actual virus. Now two new research led by TSRI scientists advance these efforts. The primary describes a technique to stabilize an essential HIV construction and doubtlessly create HIV lookalikes for large-scale vaccine manufacturing. The second research engineers novel nanoparticles as vaccine candidates, utilizing this new i...